API Documentation

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{
  "meta": {
    "created_on": "2019-09-13 11:49:13.442563",
    "server_url": "http://harrier.nagahama-i-bio.ac.jp/dtx/"
  },
  "data": [
    {
      "symbol": "PDCD1",
      "name": "programmed cell death 1",
      "entrez_id": "5133",
      "rating": {
        "rank_nethub": 81.5385416124499,
        "rank_omim": 96.00791131005049,
        "rank_gwas": 23.044292926664237,
        "rank_funct": 48.71701452141779,
        "rank_simseq": 97.33253526258264,
        "rank_nov3d": 64.46416488835683
      },
      "cov_pdb": [
        {
          "start": 1,
          "end": 24,
          "iden": 0,
          "pdb_chain": "-"
        },
        {
          "start": 25,
          "end": 142,
          "iden": 92.373,
          "pdb_chain": "5WT9[G]"
        },
        {
          "start": 143,
          "end": 288,
          "iden": 0,
          "pdb_chain": "-"
        }
      ],
      "target_drug": [
        {
          "drug_id": "D10316",
          "drug_name": "Nivolumab",
          "het_code": "-"
        },
        {
          "drug_id": "D10574",
          "drug_name": "Pembrolizumab",
          "het_code": "-"
        },
        {
          "drug_id": "D11108",
          "drug_name": "Cemiplimab",
          "het_code": "-"
        },
        {
          "drug_id": "D10390",
          "drug_name": "Pidilizumab",
          "het_code": "-"
        },
        {
          "drug_id": "D11366",
          "drug_name": "Dostarlimab",
          "het_code": "-"
        },
        {
          "drug_id": "D11487",
          "drug_name": "Tislelizumab",
          "het_code": "-"
        },
        {
          "drug_id": "D11488",
          "drug_name": "Cetrelimab",
          "het_code": "-"
        }
      ],
      "accession": "Q15116",
      "metrics": {
        "n_ppi": 52,
        "n_gwas": 0,
        "n_go": 11,
        "n_drug": 7,
        "n_omim": 2,
        "target_simil": "100.0"
      },
      "is_drug_target": true,
      "is_drugbank_approved_target": true,
      "is_drugbank_non_approved_target": true,
      "pfam": [
        {
          "accession": "PF07686.16",
          "t_name": "V-set",
          "description": "0.84 Immunoglobulin V-set domain",
          "q_start": 37,
          "q_end": 145,
          "evalue": 3.1e-15,
          "score": 56.2
        }
      ],
      "is_cancer_census": false,
      "gene_ontology": {
        "Process": [
          {
            "go_id": "GO:0002644",
            "term": "negative regulation of tolerance induction"
          },
          {
            "go_id": "GO:0006915",
            "term": "apoptotic process"
          },
          {
            "go_id": "GO:0006959",
            "term": "humoral immune response"
          },
          {
            "go_id": "GO:0007275",
            "term": "multicellular organism development"
          },
          {
            "go_id": "GO:0031295",
            "term": "T cell costimulation"
          },
          {
            "go_id": "GO:0043066",
            "term": "negative regulation of apoptotic process"
          },
          {
            "go_id": "GO:0070234",
            "term": "positive regulation of T cell apoptotic process"
          }
        ],
        "Function": [
          {
            "go_id": "GO:0005515",
            "term": "protein binding"
          }
        ],
        "Component": [
          {
            "go_id": "GO:0005886",
            "term": "plasma membrane"
          },
          {
            "go_id": "GO:0009897",
            "term": "external side of plasma membrane"
          },
          {
            "go_id": "GO:0016021",
            "term": "integral component of membrane"
          }
        ]
      },
      "omim_phenotype": [
        {
          "omim_id": 126200,
          "title": "MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO; MS"
        },
        {
          "omim_id": 605218,
          "title": "SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 2; SLEB2"
        }
      ],
      "category": [
        "CellSurfaceMolecule"
      ],
      "tsc30": "0.41",
      "tsc90": "0.41",
      "idg": {
        "idgTDL": "Tclin",
        "idgFamily": "Non-IDG"
      }
    }
  ]
}