Predict domain-domain interface
PreDom:Interface predicts domain-domain interaction residues from the 3D structure of domain. Domain interface residues are predicted by two algorithm; KIP and IP.
- KIP (Known Interface residue Positions): Domain interface residues are predicted using the positions of known domain interface residues in homologous domains(in SCOP or CATH).
- IP (Interface Propensity): Domain interface residues are predicted using the prediction score calculated from interface propensity, which means usage preference in domain-domain interfaces compared to the other part of domain surface. To increase the specificity of prediction, two interface propensities, "core" and "peripheral", are used for the score calculation.